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  • Monday 21 Sep 2020

    A recent study published on the preprint server bioRxiv* seeks to establish the pattern of antibody reactivity in COVID-19 convalescent plasma (CCP), which is widely being used as a therapy for seriously ill COVID-19 patients.

  • Sunday 20 Sep 2020

    Primary Sjogren syndrome is a systemic autoimmune disease with a possible lung involvement, that it appears as polymorphic, including interstitial lung disease, airway disease and lymphoproliferative disorders with different degree of severity buff.ly/32OrArQ

    Primary Sjogren syndrome (pSS) is a systemic autoimmune disease characterised by lymphocytic infiltration of exocrine glands and by a number of systemic manifestations, including those regarding the lung. Pulmonary involvement in pSS includes interstitial lung disease (ILD) and airway disease, toget...

  • Saturday 19 Sep 2020

    Chronic obstructive pulmonary disease (COPD) is characterised by progressive airflow limitation and chronic inflammation. Predicting exacerbations of COPD, which contribute to disease progression, is important to guide preventative treatment and improve outcomes. Blood eosinophils are a biomarker fo...

  • Saturday 19 Sep 2020

    In a high-prevalence emergency department setting, chest CT showed a high probability of COVID19 in 30% of patients with a negative or indeterminate initial RT-PCR result buff.ly/2ZQlMfo

    Since the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, clinicians have been struggling with the optimal diagnostic approach of suspected patients. Real-time reverse transcriptase-polymerase chain reaction (RT-PCR) testing of respiratory samples is generally being considered as the r...

  • Saturday 19 Sep 2020

    Humoral immune response to SARSCoV2 showed an early response of IgA, instead of IgM, in COVID19 patients. As highlighted by this study, enhanced IgA responses observed in severe COVID-19 might confer damaging effects in severe COVID-19. buff.ly/3mAqEPz

    In comparison to severe acute respiratory syndrome coronavirus (SARS-CoV), SARS-CoV-2 appears to be more contagious [1], and coronavirus disease 2019 (COVID-19) patients demonstrate varied clinical manifestations distinct from those seen in patients with SARS-CoV and Middle East respiratory syndrome...

  • Friday 18 Sep 2020

    Pneumothorax in COVID-19 disease- incidence and clinical characteristics

    "A blog about allergy, asthma & immunology"

  • Friday 18 Sep 2020

    Apple, Anthem launch 2-year study of asthma app, connected devices buff.ly/2FEvSsM via @MobiHealthNews

    The 900-participant study uses learnings from Apple's Tueo Health acquisition and could inform the development of a digital biomarker for asthma.

  • Friday 18 Sep 2020

    Distinct effects of asthma and COPD comorbidity on disease expression and outcome in patients with COVID-19. Corresponding Author: Yang Liu, Jun‐Gang Xie, Zheng Liu; Download Article Here: buff.ly/3bZlFDj

    After adjusting for confounding factors, COVID‐19 patients with COPD have higher risks of developing severe illness and acute respiratory distress syndrome than COVID‐19 patients with asthma. COPD pa...

  • Friday 18 Sep 2020

    An internationally validated model, nomogram, and online calculator for severity risk assessment and triage of #COVID19 patients at hospital admission buff.ly/3cfbRFi

    Background The outbreak of coronavirus disease 2019 (COVID-19) has globally strained medical resources and caused significant mortality. Objective To develop and validate a machine-learning model based on clinical features for severity risk assessment and triage for COVID-19 patients at hospital adm...

  • Thursday 17 Sep 2020

    Randomized Trial of Nocturnal Oxygen in COPD This is an underpowered trial that provides no indication that nocturnal oxygen has a positive or negative effect on survival or progression to long-term oxygen therapy in patients with COPD. The efficacy of long-term oxygen therapy (LTOT) for the management of isolated nocturnal hypoxemia is uncertain. Patients with an oxygen saturation <90% for at least 30% of the recording time on nocturnal oximetry were assigned, in a 1:1 ratio, to receive either nocturnal oxygen or ambient air from a sham concentrator (placebo). The primary outcome was a composite of death from any cause or a requirement for long-term oxygen therapy as defined by the Nocturnal Oxygen Therapy Trial (NOTT) criteria in the intention-to-treat population. Recruitment was stopped prematurely because of recruitment and retention difficulties after 243 patients, of a projected 600, had undergone randomization at 28 centers. At 3 years of follow-up, 39.0% of the patients assigned to nocturnal oxygen (48 of 123) and 42.0% of those assigned to placebo (50 of 119) met the NOTT-defined criteria for long-term oxygen therapy or had died (difference, −3.0 percentage points; 95% confidence interval, −15.1 to 9.1).

    Original Article from The New England Journal of Medicine — Randomized Trial of Nocturnal Oxygen in Chronic Obstructive Pulmonary Disease

  • Thursday 17 Sep 2020

    What is New in Respiratory Medicine Ioannina 2020 #WiNRespMed September 18-20, 2020, Ioannina-Greece. In response to the COVID-19 pandemic, the Organizing Committee, the Congress Administration and the Congress Venue are committed to implement the measures recommended by the health authorities and the Government. We will make every effort to make this hybrid event scientifically rewarding and memorable to all of you. Gain access to watch on line https://academy.respiratory-ioannina.com Download the WiNRespMed app and carry the congress in your pocket. https://bit.ly/2ZJHeCy Find more about the program: https://respiratory-ioannina.com/winrespmed2020

  • Thursday 17 Sep 2020

    COVID-19 in a patient with recent liver transplantation

    Case Records of the Massachusetts General Hospital from The New England Journal of Medicine — Case 29-2020: A 66-Year-Old Man with Fever and Shortness of Breath after Liver Transplantation

  • Thursday 17 Sep 2020

    After screening more than 3,500 FDA-approved drugs and small molecules, researchers at the Chinese Academy of Sciences found that ceftazidime, an antibiotic approved for use in treating pneumonia, binds to the receptors that the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) binds to i...

  • Thursday 17 Sep 2020

    Test your knowledge of the COVID-19

  • Wednesday 16 Sep 2020

    It tends to become a joke, one day vit D plays an important role, and the other day it doesn't! Thankfully I don 't really have to worry about this, although all of my patients have low levels or even defficiency of vit D, family doctors always test it and always give a supplement, patients just inform me.

    Adults with vitamin D deficiency are at greater risk for severe COVID-19 infection and death, according to data presented at the American Society for Bone and Mineral Research virtual meeting.“Vitamin D deficiency is common in most countries, particularly during the winter season,” Luigi...

  • Wednesday 16 Sep 2020

    Mortality and morbidity in obstructive sleep apnoea–hypopnoea syndrome: results from a 30-year prospective cohort study.

    Long-term CPAP use in men and women with obstructive sleep apnoea–hypopnoea syndrome (OSAHS) reduces mortality and decreases the incidence of DMII and cardiovascular disease.

    Background Obstructive sleep apnoea–hypopnoea syndrome (OSAHS) carries substantial negative health consequences. This study examines factors affecting mortality and morbidity according to continuous positive airway pressure (CPAP) use and predictors affecting CPAP adherence in a longitudinal cohor...

  • Wednesday 16 Sep 2020

    Asthma among hospitalized patients with COVID-19 and related outcomes.

    Among hospitalized patients 65 years or younger with severe COVID-19, asthma diagnosis was not associated with worse outcomes, regardless of age, obesity, or other high-risk comorbidities.

    Several underlying conditions have been associated with severe acute respiratory syndrome coronavirus 2 illness, but it remains unclear whether underlying asthma is associated with worse coronavirus disease 2019 (COVID-19) outcomes.

  • Wednesday 16 Sep 2020

    Es una publicacion muy imortante. Nuestro Patrimonio

    Institución dedicada a la gestión profesional de proyectos de preservación del patrimonio cultural nacional

  • Wednesday 16 Sep 2020

    Somatotypes trajectories during adulthood and their association with COPD phenotypes.

    COPD patients have distinct somatotype trajectories throughout adulthood. Those with the multiple organ loss of tissue (MOLT) phenotype maintain a lean trajectory throughout life. Smoking subjects with this lean phenotype in early adulthood deserve particular attention as they seem to develop more severe COPD.

    Rationale Chronic obstructive pulmonary disease (COPD) comprises distinct phenotypes, all characterised by airflow limitation. Objectives We hypothesised that somatotype changes – as a surrogate of adiposity – from early adulthood follow different trajectories to reach distinct phenotypes. Metho...

  • Wednesday 16 Sep 2020

    Cigarette-related cadmium and environmental pollution exposure are reflected in airway ultrafine particle content.

    Low ultrafine particle (UFP) concentration in exhaled breath condensate (EBC) is an indicator of high-level particulate matter (PM) exposure. High cadmium levels in EBC among smokers and the association between cadmium and UFP content in EBC among COPD patients indicate cadmium lung toxicity.

    Introduction Particulate matter (PM) and cigarette-related cadmium exposure increases inflammation and smokers' susceptibility to developing lung diseases. The majority of inhaled metals are attached to the surface of ultrafine particles (UFPs). A low inhaled UFP content in exhaled breath condensate...

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